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Friday, 17 February 2012

Visual Pathway Axonal Loss in Benign Multiple Sclerosis: A Longitudinal Study.

Benign MS - A type of relapsing-remitting multiple sclerosis in which few relapses occur. The relapses tend to produce sensory symptoms, which go away and leave very little, or no residual damage or disability.
However, people with “Benign MS” have RNFL axonal loss that is as marked as that of typical MS and have reduced vision and quality of life. While overall neurologic impairment is mild, visual dysfunction, not well captured by the EDSS, accounts for a substantial degree of disability in benign MS.
Benign multiple sclerosis is traditionally defined as Expanded Disability Status Scale (EDSS) score ≤3 and ≥15-year disease duration, and is thought to follow a milder clinical course
It describes the problem in those who have had MS for fifteen or more years without picking up any enduring disability, with negligible neurological symptoms and no serious or continuing disabilities.
Usually those classified with Benign MS have mild, infrequent, sensory exacerbations with a full recovery.
Benign MS may only be positively identified after there is minimal disability 10 to 15 years following its official onset.
Some classified with Benign MS will eventually experience disease progression; their course of disease may change and evolve into the progressive stage of MS.
Benign multiple sclerosis is one of the least common forms of the disease.http://www.proventus.org.uk/page647.html

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